ZBTB5 Polyclonal Antibody Reactivity Human
SKU: E-AB-52367-200
ZBTB5 Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52367 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human ZBTB5 |
| Abbre | ZBTB5 |
| Synonyms | 5930421I10, 9430083K24Rik, AI646847, Expressed in brain and neural tube, KIAA0354, OTTMUSP00000007812, OTTMUSP00000007813, OTTMUSP00000007814, RP11-397D12.5, RP23-218A4.2, Transcription factor ZNF POZ, ZBTB5, Zbtb5, Zinc finger and BTB domain containing prot, mKIAA0354 |
| Swissprot | |
| Calculated MW | 74 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Nucleus. |
| Concentration | 0.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
Background
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger and BTB domain-containing protein 5 (ZBTB5) is a 677 amino acid member of the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZBTB5 contains a BTB domain, also known as a POZ domain, which inhibits DNA binding and mediates homotypic and heterotypic dimerization. Characteristics of the BTB domain suggest that ZBTB5 functions as a transcription regulator.