UHRF2 Polyclonal Antibody Store at -20°C
SKU: E-AB-13450-200
UHRF2 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-13450 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human UHRF2 |
| Abbre | UHRF2 |
| Synonyms | DKFZp434B0920, DKFZp686G0837, E3 ubiquitin-protein ligase UHRF2, MGC33463, Np95 like RING finger protein, Np95-like ring finger protein, Np95/ICBP90 like RING finger protein, Np95/ICBP90-like RING finger protein, Nuclear protein 97, Nuclear zinc finger protein Np9 |
| Swissprot | |
| Cellular Localization | Nucleus. |
| Concentration | 0.8 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding.