UBE2V1 Polyclonal Antibody Reactivity Human
SKU: E-AB-52433-200
UBE2V1 Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52433 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Full length fusion protein |
| Abbre | UBE2V1 |
| Synonyms | CIR1, CROC-1, CROC1, CROC1A, TRAF6-regulated IKK activator 1 beta Uev1A, UB2V1, UBE2V, UBE2V 1, UBE2V1, UEV-1, UEV1, Ubiquitin conjugating enzyme E2 variant 1, Ubiquitin-conjugating enzyme E2 variant 1 |
| Swissprot | |
| Calculated MW | 16 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Nucleus. Excluded from the nucleolus. |
| Concentration | 0.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cell Biology, Epigenetics and Nuclear Signaling, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:30-1:150 |
Background
Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family.They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s.The protein encoded by this gene is located in the nucleus and can cause transcriptional activation of the human FOS proto-oncogene.It is thought to be involved in the control of differentiation by altering cell cycle behavior.Alternatively spliced transcript variants encoding multiple isoforms have been described for this gene, and multiple pseudogenes of this gene have been identified.Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (Kua-UEV), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.