UBE2E3 Polyclonal Antibody
SKU: E-AB-52434-200
UBE2E3 Polyclonal Antibody
| SKU # | E-AB-52434 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human UBE2E3 |
| Abbre | UBE2E3 |
| Synonyms | Homologous to yeast UBC4/5, UB2E3, UBC E4, UBC4/5 homolog, UBCE 4, UBCE4, UBCH 9, UBE2 E3, UBE2E3, Ubc M2, UbcH9, UbcM2, Ubiquitin carrier protein, Ubiquitin carrier protein E3, Ubiquitin conjuga, Ubiquitin conjugating enzyme E2 23 kDa, Ubiquitin conjugating enzyme E2 E3 |
| Swissprot | |
| Cellular Localization | Nucleus. Cytoplasm. Shuttles between the nucleus and cytoplasm in a IPO11-dependent manner. |
| Concentration | 0.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cell Biology, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:30-1:150 |
Background
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse and rat counterparts, which indicates that this enzyme is highly conserved in eukaryotes. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.