TRAF3IP2 Polyclonal Antibody Store at -20°C
SKU: E-AB-10655-200
TRAF3IP2 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-10655 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human TRAF3IP2 |
| Abbre | TRAF3IP2 |
| Synonyms | ACT1, Act 1, Activator of cAMP responsive element modulator (CREM) in testis, Adapter protein CIKS, C6ORF4, C6ORF5, C6ORF6, CIKS, Chromosome 6 Open Reading Frame 4, Chromosome 6 Open Reading Frame 5, Chromosome 6 Open Reading Frame 6, Connection to IKK and SAPK / JN |
| Swissprot | |
| Calculated MW | 65 kDa |
| Cellular Localization | Other locations: intracellular. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:200-1:1000 |
| IHC | 1:25-1:100 |
Background
This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Several alternative transcripts encoding different isoforms have been identified. Another transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene.