TP53BP2 Polyclonal Antibody Store at -20°C
SKU: E-AB-14774-200
TP53BP2 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-14774 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human TP53BP2 |
| Abbre | TP53BP2 |
| Synonyms | 53BP2, ASPP2, Apoptosis stimulating of p53 protein 2, Apoptosis stimulating protein of p53 2, Apoptosis-stimulating of p53 protein 2, BBP, Bcl2 binding protein, Bcl2-binding protein, NY REN 51 antigen, PPP1R, p53 binding protein 2, p53-binding protein 2, p53BP2 |
| Swissprot | |
| Calculated MW | 126 kDa |
| Cellular Localization | Cytoplasm>perinuclear region. Nucleus. Predominantly found in the perinuclear region. Some small fraction is nuclear. Sequester in the cytoplasm on overexpression of DDX42. |
| Concentration | 0.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cell Biology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:50-1:200 |
Background
This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different isoforms have been found for this gene.