TM7SF2 Polyclonal Antibody Store at -20°C
SKU: E-AB-13736-200
TM7SF2 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-13736 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human TM7SF2 |
| Abbre | TM7SF2 |
| Synonyms | ANG1, DHCR14A, NET47 |
| Swissprot | |
| Calculated MW | 46 kDa |
| Cellular Localization | Endoplasmic reticulum, endoplasmic reticulum, endoplasmic reticulum membrane, integral component of endoplasmic reticulum membrane, Plasma Membrane, integral component of plasma membrane, Other locations: intracellular membrane-bounded organelle, organelle membrane, receptor complex. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
Background
Transmembrane 7 superfamily member 2 (TM7SF2, Sterol C14-reductase, 3beta-hydroxysterol Delta-reductase) is a 418 amino acid gene product that belongs to the ERG4/ERG24 family. TM7SF2 is a seven pass transmembrane protein that can localize to the membrane of the endoplasmic reticulum. TM7SF2 is involved in the conversion of lanosterol to cholesterol and, specifically, catalyzes the NADPH dependant reduction of 4,4-dimethyl-5-alpha-cholesta-8,14,24-trien-3-beta-ol to 4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol and NADP+.