TERF1 Polyclonal Antibody Reactivity Mouse
SKU: E-AB-52119-200
TERF1 Polyclonal Antibody Reactivity Mouse
| SKU # | E-AB-52119 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human TERF1 |
| Abbre | TERF1 |
| Synonyms | NIMA interacting protein 2, NIMA-interacting protein 2, PIN 2, PIN2, T, Telomeric protein Pin2, Telomeric protein Pin2/TRF1, Telomeric repeat binding factor (NIMA interacting) 1, Telomeric repeat binding factor 1, Telomeric repeat binding protein 1, hTRF1 AS, t TRF1 |
| Swissprot | |
| Calculated MW | 50 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Nucleus. Cytoplasm>cytoskeleton>spindle. Chromosome>telomere. Colocalizes with telomeric DNA in interphase and metaphase cells and is located at chromosome ends during metaphase. Associates with the mitotic spindle. |
| Concentration | 1.26 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling, Tags and Cell Markers |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:1000-1:5000 |
Background
This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex.This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends.The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus.Two transcripts of this gene are alternatively spliced products.