α-SMA Polyclonal Antibody
SKU: E-AB-34268-200
α-SMA Polyclonal Antibody
| SKU # | E-AB-34268 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC-p, IF |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC-p, IF |
| Clonality | Polyclonal |
| Immunogen | Synthesized peptide derived from α-SMA |
| Abbre | α-SMA |
| Synonyms | AAT6, ACTA, ACTA2, ACTSA, ACTVS, Actin, Actin alpha 2 smooth muscle aorta, Actin aortic smooth muscle, Alpha 2 actin, Alpha actin 2, Alpha cardiac actin, Alpha-actin-2, Cell growth inhibiting gene 46 protein, Cell growth-inhibiti, a actin, alpha sma, aortic smooth muscle |
| Swissprot | |
| Calculated MW | 42 kDa |
| Observed MW | 42 kDa |
| Cellular Localization | Cytoskeleton, actin filament, cytoskeleton, filamentous actin, Cytosol, Extracellular region or secreted, blood microparticle, extracellular exosome, extracellular matrix, extracellular space, Nucleus, Plasma Membrane, Other locations: dense body, focal adhesion, membrane, myelin sheath, myofibril, phagocytic vesicle. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cardiovascular, Developmental Biology, Signal Transduction, Stem Cells |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-2000 |
| IHC | 1:50-300 |
| IF | 1:50-1:200 |
Background
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. ACTA2 (Actin, Alpha 2, Smooth Muscle, Aorta) is a Protein Coding gene. Diseases associated with ACTA2 include Multisystemic Smooth Muscle Dysfunction Syndrome and Moyamoya Disease 5. Among its related pathways are ICos-ICosL Pathway in T-Helper Cell and GPCR Pathway. GO annotations related to this gene include protein kinase binding. An important paralog of this gene is ACTG2. ACTA1 (Actin, Alpha 1, Skeletal Muscle) is a Protein Coding gene. Diseases associated with ACTA1 include Nemaline Myopathy 3, Autosomal Dominant Or Recessive and Myopathy, Congenital, With Fiber-Type Disproportion. Among its related pathways are ICos-ICosL Pathway in T-Helper Cell and GPCR Pathway. GO annotations related to this gene include structural constituent of cytoskeleton and myosin binding. An important paralog of this gene is ACTC1. ACTG2 (Actin, Gamma 2, Smooth Muscle, Enteric) is a Protein Coding gene. Diseases associated with ACTG2 include Visceral Myopathy and Chronic Intestinal Pseudoobstruction. Among its related pathways are ICos-ICosL Pathway in T-Helper Cell and GPCR Pathway. An important paralog of this gene is ACTA2.