SERPINB2 Polyclonal Antibody Host Rabbit
SKU: E-AB-40447-200
SERPINB2 Polyclonal Antibody Host Rabbit
| SKU # | E-AB-40447 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant Mouse Plasminogen activator inhibitor 2, macrophage protein |
| Abbre | SERPINB2 |
| Synonyms | Monocyte Arg serpin, PAI, PAI2, PLANH2, Placental plasminogen activator inhibitor, Plasminogen activator inhibitor 2, Serpin B2, Serpinb2, Urokinase inhibitor, HsT1201 |
| Swissprot | |
| Calculated MW | 46 kDa |
| Observed MW | 46 kDa |
| Cellular Localization | Cytoplasm, Secreted. |
| Concentration | 1 mg/mL |
| Buffer | PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4 |
| Purification Method | Antigen Affinity Purification |
| Research Areas | Immunology, Cell Biology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1000 |
| IHC | 1:50-1:200 |
Background
Plasminogen activator inhibitor-2 (placental PAI) is a coagulation factor that inactivates tPA and urokinase. It is present in most cells, especiallymonocytes/macrophages. PAI-2 exists in two forms, a 60-kDa extracellular glycosylated form and a 43-kDa intracellular form. It is present only at detectable quantities in blood during pregnancy, as it is produced by the placenta, and may explain partially the increased rate of thrombosis during pregnancy.