RIC3 Polyclonal Antibody
SKU: E-AB-52913-200
RIC3 Polyclonal Antibody
| SKU # | E-AB-52913 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human RIC3 |
| Abbre | RIC3 |
| Synonyms | AYST720, FLJ11608, PRO1385, Protein RIC-3, RIC3, RIC3 acetylcholine receptor chaperone, Resistance to inhibitors of cholinesterase 3 homolog, Resistant to inhibitor of cholinesterase 3, Ric3 |
| Swissprot | |
| Cellular Localization | Endoplasmic reticulum membrane and Endoplasmic reticulum membrane. Golgi apparatus membrane. |
| Concentration | 1.56 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:300 |
Background
This gene encodes a member of the resistance to inhibitors of cholinesterase 3-like family which functions as a chaperone of specific 5-hydroxytryptamine type 3 receptor and nicotinic acetylcholine receptor subtypes. The encoded protein influences the folding and assembly of these receptor subunits in the endoplasmic reticulum and expression on the cell surface. This protein contains an N-terminal transmembrane domain, a proline-rich spacer, and a cytosolic C-terminal coiled-coil domain. Alternative splicing results in multiple transcript variants.