Recombinant Mouse TRAIL protein(N-His)(active)
SKU: PKSM041490-100
Recombinant Mouse TRAIL protein(N-His)(active)
| SKU # | PKSM041490 |
| Expression Host | E.coli |
Description
| Synonyms | FIL1ε (FIL1E), Fi, Fil, Fil1, IL-1, IL-1H1, IL1RP2, IL36A, Interleukin-1 family member 6 (IL-1F6), Interleukin-1ε (IL1E) |
| Species | Mouse |
| Expression Host | E.coli |
| Sequence | Pro 117-Asn 291 |
| Accession | P50592 |
| Calculated Molecular Weight | 21.0 kDa |
| Observed Molecular Weight | 17-25 kDa |
| Tag | C-His |
| Bio-activity | Measure by its ability to induce cytotoxicity in L929 cells in the presence of actinomycin D.The ED50 for this effect is <1 ng/mL. |
Properties
| Purity | > 98 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 0.1 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis.