RAB6A Polyclonal Antibody Store at -20°C
SKU: E-AB-12261-200
RAB6A Polyclonal Antibody Store at -20°C
| SKU # | E-AB-12261 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human RAB6A |
| Abbre | RAB6A |
| Synonyms | GTP binding protein RAB6A', GTP binding protein RAB6B, Oncogene RAB6, RAB6, RAB6 member RAS oncogene family, RAB6A, RAB6A member RAS oncogene family, RAB6A', RAB6B, Rab 6, Rab GTPase, Rab-6, Rab6A variant 3, Ras related protein Rab 6A, Ras-related protein Rab-6A |
| Swissprot | |
| Calculated MW | 24 kDa |
| Cellular Localization | Golgi apparatus membrane. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
Background
This gene encodes a member of the RAB family, which belongs to the small GTPase superfamily. GTPases of the RAB family bind to various effectors to regulate the targeting and fusion of transport carriers to acceptor compartments. This protein is located at the Golgi apparatus, which regulates trafficking in both a retrograde (from early endosomes and Golgi to the endoplasmic reticulum) and an anterograde (from the Golgi to the plasma membrane) directions. Myosin II is an effector of this protein in these processes. This protein is also involved in assembly of human cytomegalovirus (HCMV) by interacting with the cellular protein Bicaudal D1, which interacts with the HCMV virion tegument protein, pp150. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.