POMC Polyclonal Antibody Reactivity Mouse
SKU: E-AB-40635-100
POMC Polyclonal Antibody Reactivity Mouse
| SKU # | E-AB-40635 |
| Reactivity | mouse, Rat |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Mouse, Rat |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide. |
| Abbre | POMC |
| Synonyms | ACTH, Alpha-MSH, Beta-LPH, Beta-MSH, Beta-endorphin, CLIP, Corticotropin, Corticotropin-lipotropin, Gamma-LPH, Gamma-MSH, Melanotropin gamma, Met-enkephalin, NPP, Potential peptide, Pro-opiomelanocortin |
| Swissprot | |
| Calculated MW | 29 kDa |
| Observed MW | 35 kDa, 16 kDa |
| Cellular Localization | Secreted |
| Concentration | 1 mg/mL |
| Buffer | PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4 |
| Purification Method | Antigen Affinity Purification |
| Research Areas | Cancer, Metabolism, Neuroscience, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:1000-1:2000 |
Background
Pro-opiomelanocortin (POMC) is a precursor protein expressed in the pituitary and the brain where it is processed into several peptide hormones and neuropeptides. Among these peptides are ACTH,α- and β-MSH,β-and γ-LPH,CLIP,β-endorphin,and N-POMC. POMC is involved in hypothalamic circuits regulating feeding behavior and POMC-producing neurons promote satiety. POMC neurons are also the target of leptin and insulin for the promotion of the browning of white fat.