PHF6 Polyclonal Antibody
SKU: E-AB-52168-200
PHF6 Polyclonal Antibody
| SKU # | E-AB-52168 |
| Reactivity |
Human, Mouse |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human PHF6 |
| Abbre | PHF6 |
| Synonyms | AC004383.6, BFLS, BORJ, CENP 31, Centromere protein 31, MGC14797, OTTHUMP00000024063, PHD finger protein 6, PHD like zinc finger protein, PHD-like zinc finger protein, PHF6, Phf6 |
| Swissprot | |
| Cellular Localization | Nucleus. Nucleus>nucleolus. Nuclear, it particularly localizes to the nucleolus. |
| Concentration | 1.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:100-1:300 |
Background
This gene is a member of the plant homeodomain (PHD)-like finger (PHF) family.It encodes a protein with two PHD-type zinc finger domains, indicating a potential role in transcriptional regulation, that localizes to the nucleolus.Mutations affecting the coding region of this gene or the splicing of the transcript have been associated with Borjeson-Forssman-Lehmann syndrome (BFLS), a disorder characterized by cognitive disability, epilepsy, hypogonadism, hypometabolism, obesity, swelling of subcutaneous tissue of the face, narrow palpebral fissures, and large ears.Alternate splicing results in multiple transcript variants, encoding different isoforms.