OTUB1 Polyclonal Antibody Store at -20°C
SKU: E-AB-11463-200
OTUB1 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-11463 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human OTUB1 |
| Abbre | OTUB1 |
| Synonyms | Deubiquitinating enzyme OTUB1, HSPC263, OTB1, OTU, OTU domain, OTU domain containing ubiquitin aldehyde binding protein 1, OTU domain-containing Ubal-binding protein 1, OTU domain-containing ubiquitin aldehyde-binding protein 1, hOTU1, ubiquitin aldehyde binding 1 |
| Swissprot | |
| Calculated MW | 31 kDa |
| Cellular Localization | Cytoplasm. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
Background
The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases.The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates.It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system.It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth.