NDUFS2 Polyclonal Antibody Store at -20°C
SKU: E-AB-13445-200
NDUFS2 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-13445 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human NDUFS2 |
| Abbre | NDUFS2 |
| Synonyms | 49 KD subunit, 49kDa (NA, CI 49, CI 49kD, CI-49kD, Complex 1, Complex I 49kD, Complex I 49kDa subunit, Complex I-49kD, NADH dehydrogenase (ubiquinone) Fe S protein 2, NADH dehydrogenase (ubiquinone) Fe S protein 2 49kDa, mitochondrial, mitochondrial respiratory chain |
| Swissprot | |
| Calculated MW | 53 kDa |
| Cellular Localization | Mitochondrion inner membrane. |
| Concentration | 0.7 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Metabolism, Signal Transduction, Tags and Cell Markers |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:200-1:1000 |
| IHC | 1:50-1:200 |
Background
The protein encoded by this gene is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I). Mammalian mitochondrial complex I is composed of at least 43 different subunits, 7 of which are encoded by the mitochondrial genome, and the rest are the products of nuclear genes. The iron-sulfur protein fraction of complex I is made up of 7 subunits, including this gene product. Complex I catalyzes the NADH oxidation with concomitant ubiquinone reduction and proton ejection out of the mitochondria. Mutations in this gene are associated with mitochondrial complex I deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.