MYO7A Polyclonal Antibody Store at -20°C
SKU: E-AB-13433-200
MYO7A Polyclonal Antibody Store at -20°C
| SKU # | E-AB-13433 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human MYO7A |
| Abbre | MYO7A |
| Synonyms | DFNA11, DFNB 2, DFNB2, Deafness autosomal dominant 11, Deafness autosomal recessive 2, MYOVIIA, MYU7A, Myo7a, Myosin, Myosin 7a, Myosin VIIA (Usher syndrome 1B (autosomal recessive, Myosin VIIa, NSRD 2, NSRD2, Unconventional , family VII, member A, severe)), unconventional |
| Swissprot | |
| Cellular Localization | Cytoplasmic, cytoskeleton. |
| Concentration | 0.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:25-1:100 |
Background
This gene is a member of the myosin gene family. Myosins are mechanochemical proteins characterized by the presence of a motor domain, an actin-binding domain, a neck domain that interacts with other proteins, and a tail domain that serves as an anchor. This gene encodes an unconventional myosin with a very short tail. Defects in this gene are associated with the mouse shaker-1 phenotype and the human Usher syndrome 1B which are characterized by deafness, reduced vestibular function, and (in human) retinal degeneration. Alternative splicing results in multiple transcript variants.