MUTYH Polyclonal Antibody Store at -20°C
SKU: E-AB-10477-200
MUTYH Polyclonal Antibody Store at -20°C
| SKU # | E-AB-10477 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human MUTYH |
| Abbre | MUTYH |
| Synonyms | A/G specific adenine DNA glycosylase, A/G-specific adenine DNA glycosylase, Adenine DNA glycosylase, CYP2C, E. coli, MGC4416, MUTYH, MYH, MutY, MutY (E. coli) homolog, MutY homolog, MutY homolog (E. coli), Mutyh, hMYH, homolog of, rMYH |
| Swissprot | |
| Calculated MW | 60 kDa |
| Cellular Localization | Nucleus. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:1000-1:5000 |
| IHC | 1:50-1:200 |
Background
This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene.