MSE PRO N-Boc-6-hydroxy-3-azabicyclo[3.3.0]octane, ≥98.0% Purity - MSE Supplies LLC

MSE PRO N-Boc-6-hydroxy-3-azabicyclo[3.3.0]octane, ≥98.0% Purity

SKU: CM1392

  • $ 29495
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 MSE PRO™ N-Boc-6-hydroxy-3-azabicyclo[3.3.0]octane, ≥98.0% Purity

MSE PRO™ N-Boc-6-hydroxy-3-azabicyclo[3.3.0]octane offers a multifaceted and beneficial role as a heterocyclic building block in both organic synthesis and medicinal chemistry. Its distinctive bicyclic structure includes a bridgehead nitrogen and a hydroxyl group, while the Boc protecting group allows for targeted functionalization. This compound also serves as a potential intermediate for the creation of intricate nitrogen-containing molecules.

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Technical Specifications:

CAS No. 130658-13-8
Chemical name N-Boc-6-hydroxy-3-azabicyclo[3.3.0]octane
  • 4-Hydroxy-hexahydro-cyclopenta[c]pyrrole-2-carboxylic acid tert-butyl ester
  • tert-Butyl 4-hydroxyhexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate
Molecular formula C12H21NO3      
Pack size 1 g (CM1392); 5 g (CM1393)
Molecular weight 227.30 g/mol
Purity ≥98.0% (NMR) 
Boiling point  327.9±25.0 °C (Predicted)
Density   1.146±0.06 g/cm3 (Predicted)
pKa 14.95±0.20 (Predicted)
Appearance White to off-white solid 
Storage  Store at room temperature


[1] Bunch, L., Nielsen, B., Jensen, A. A., & Bräuner-Osborne, H. (2006). Rational Design and Enantioselective Synthesis of (1 R, 4 S, 5 R, 6 S)-3-Azabicyclo [3.3. 0] octane-4, 6-dicarboxylic Acid A Novel Inhibitor at Human Glutamate Transporter Subtypes 1, 2, and 3. Journal of medicinal chemistry49(1), 172-178.

[2] Franzyk, H., Frederiksen, S. M., & Jensen, S. R. (2000). Conversion of the iridoid glucoside antirrhinoside into 3-azabicyclo [3.3. 0] octane building blocks. Journal of Natural Products63(5), 592-595.