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MSE PRO Bis(di-tert-butyl)-4-dimethylaminophenylphosphine (Amphos), 98% Purity - MSE Supplies LLC

MSE PRO Bis(di-tert-butyl)-4-dimethylaminophenylphosphine (Amphos), 98% Purity

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MSE PRO™ Bis(di-tert-butyl)-4-dimethylaminophenylphosphine (Amphos), 98% Purity

MSE PRO™ Bis(di-tert-butyl)-4-dimethylaminophenylphosphine (Amphos) is a highly versatile ligand and can be used with a variety of substrates and catalytic systems, making it ideal for a wide range of coupling reactions, such as Buchwald-Hartwig cross coupling, Suzuki-Miyaura coupling, Stille coupling, Sonogashira coupling, Negishi coupling, Heck coupling, and Hiyama coupling. With a purity of 98%, this product is a top choice for industry seeking reliable and effective results in their synthesis reactions.

MSE Supplies offers various catalysts and ligands of coupling reaction. Please contact us for customization or bulk orders.

Technical Specifications:

CAS No. 932710-63-9
Chemical name  Bis(di-tert-butyl)-4-dimethylaminophenylphosphine
Synonym(s)
  • Amphos
  • 2-Dicyclohexylphosphino-2',4',6'-triisopropyl-3,6-diMethoxybiphenyl
Molecular formula C16H28NP
Pack size

10 g (CM1337); 25 g (CM1338)

Molecular weight 265.37 g/mol
Purity 98 %
Melting point 57-61 °C
Solubility
Soluble in Acetone
Appearance White solid
Storage  Keep in dark place, inert atmosphere, room temperature


References:

[1] Kosaka, Kentaro, et al. "AmPhos Pd-Catalyzed Suzuki–Miyaura Catalyst-Transfer Condensation Polymerization: Narrower Dispersity by Mixing the Catalyst and Base Prior to Polymerization." Macromolecules 51.2 (2018): 364-369.

[2] Tanimoto, H., Adachi, R., Tanisawa, K., & Tomohiro, T. (2024). Amphos-Mediated Conversion of Alkyl Azides to Diazo Compounds and One-Pot Azide-Site Selective Transient Protection, Click Conjugation, and Deprotective Transformation. Organic Letters.