MPP1 Polyclonal Antibody Reactivity Human
SKU: E-AB-52967-200
MPP1 Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52967 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human MPP1 |
| Abbre | MPP1 |
| Synonyms | palmitoy, 55 kDa erythrocyte membrane protein, AAG 12, AAG12, Aging associated gene 12, DXS552, DXS552E, EM55, EMP 55, EMP55, Erythrocyte membrane protein p55, Membrane protein, Membrane protein palmitoylated 1, Membrane protein palmitoylated 1 55kDa |
| Swissprot | |
| Cellular Localization | Membrane. Cell projection>stereocilium. Colocalizes with WHRN at stereocilium tip during hair cell development (By similarity). Colocalizes with MPP5 in the retina, at the outer limiting membrane (OLM). Colocalizes with WHRN in the retina, at the outer limiting membrane (OLM), outer plexifirm layer (OPL), basal bodies and at the connecting cilium (CC). Colocalizes with NF2 in non-myelin-forming Schwann cells. |
| Concentration | 0.9 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cardiovascular, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:300 |
Background
This gene encodes the prototype of the membrane-associated guanylate kinase (MAGUK) family proteins.MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intercellular junctions.The encoded protein is an extensively palmitoylated membrane phosphoprotein containing a PDZ domain, a Src homology 3 (SH3) motif, and a guanylate kinase domain.This gene product interacts with various cytoskeletal proteins and cell junctional proteins in different tissue and cell types, and may be involved in the regulation of cell shape, hair cell development, neural patterning of the retina, and apico-basal polarity and tumor suppression pathways in non-erythroid cells.Multiple transcript variants encoding different isoforms have been found for this gene.