MMP13 Polyclonal Antibody Store at -20°C
SKU: E-AB-10064-200
MMP13 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-10064 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human MMP13 |
| Abbre | MMP13 |
| Synonyms | CLG 3, CLG3, Collagenase 3, Collagenase3, MANDP1, MMP 13, MMP-13, MMP13, Matrix Metalloproteinase 13, Matrix metallopeptidase 13 (collagenase 3), Matrix metalloproteinase-13, Mmp13 |
| Swissprot | |
| Calculated MW | 54 kDa |
| Cellular Localization | Secreted>extracellular space>extracellular matrix. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Cardiovascular, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
Background
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.