MAP2K6 Polyclonal Antibody Reactivity Mouse
SKU: E-AB-40167-200
MAP2K6 Polyclonal Antibody Reactivity Mouse
| SKU # | E-AB-40167 |
| Reactivity | Mouse, Rat |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant Mouse Dual specificity mitogen-activated protein kinase kinase 6 protein |
| Abbre | MAP2K6 |
| Synonyms | MAPKK6, MEK6, MKK6, PRKMK6, SAPKK-3, SAPKK3 |
| Swissprot | |
| Cellular Localization | Cytoskeleton, Cytosol, Nucleus, nucleoplasm, nucleus, Other locations: cytoplasm. |
| Concentration | 1 mg/mL |
| Buffer | PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4 |
| Purification Method | Antigen Affinity Purification |
| Research Areas | Cell Biology, Immunology, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:100 |
Background
This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.