KLK6 Polyclonal Antibody Host Rabbit
SKU: E-AB-40369-200
KLK6 Polyclonal Antibody Host Rabbit
| SKU # | E-AB-40369 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant Human Kallikrein-6 protein |
| Abbre | KLK6 |
| Synonyms | Bssp, KLK 6, KLK 9, KLK6, KLK9, Kallikrein 6 precursor, Kallikrein related peptidase 6, Kallikrein-6, Kallikrein6, Klk 7, Klk29, Klk6, Klk7, MGC9355, MSP, Neurosin, PRSS 18, PRSS 9, PRSS18, PRSS9, Protease M, Protease serine 18, Protease serine 9, Serine pro, hK 6, hK6, mGK 1, mGK1 |
| Swissprot | |
| Cellular Localization | Cytoplasm, Endoplasmic reticulum, Mitochondrion, Nucleus, Secreted. |
| Concentration | 1 mg/mL |
| Buffer | PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4 |
| Purification Method | Antigen Affinity Purification |
| Research Areas | Cancer, Neuroscience, Tags and Cell markers, Signal Transduction, Cell Biology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:100-1:300 |
Background
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene.