KDM4C Polyclonal Antibody Store at -20°C
SKU: E-AB-13351-200
KDM4C Polyclonal Antibody Store at -20°C
| SKU # | E-AB-13351 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human KDM4C |
| Abbre | KDM4C |
| Synonyms | GASC 1 protein, GASC-1 protein, GASC1, Gene amplified in squamous cell carcinoma 1 protein, J, JHDM3C, JMJD2C, JmjC domain containing histone demethylation protein 3C, JmjC domain-containing histone demethylation protein 3C, Jumonji domain containing 2C, bA146B14.1 |
| Swissprot | |
| Calculated MW | 120 kDa |
| Cellular Localization | Nucleus. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
Background
This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants.