IL5RA Polyclonal Antibody Store at -20°C
SKU: E-AB-13329-200
IL5RA Polyclonal Antibody Store at -20°C
| SKU # | E-AB-13329 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human IL5RA |
| Abbre | IL5RA |
| Synonyms | CDw, HSIL5R, IL5RA, CD125, CDw125, HSIL5R3, IL5R, IL-5 receptor subunit alpha, IL-5R subunit alpha, IL-5RA, IL-5R-alpha, Interleukin-5 receptor subunit alpha, CDw125, IL-5R&, alpha, CD125 antigen, IL5R, Interleukin 5 Receptor alpha, Interleukin 5 Receptor alpha chain, Interleukin 5 receptor alpha subunit, Interleukin 5 receptor subunit alpha, Interleukin 5 receptor type 3, MGC26560 |
| Swissprot | |
| Calculated MW | 48 kDa |
| Cellular Localization | Membrane. |
| Concentration | 0.8 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Immunology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:200-1:1000 |
| IHC | 1:50-1:200 |
Background
The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported.