HINT1 Polyclonal Antibody Store at -20°C Host Rabbit
SKU: E-AB-16478-200
HINT1 Polyclonal Antibody Store at -20°C Host Rabbit
| SKU # | E-AB-16478 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human HINT1 |
| Abbre | HINT1 |
| Synonyms | Adenosine 5' monophosphoramidase, Adenosine 5''-monophosphoramidase, HINT 1, HINT1, Histidine triad nucleotide binding protein 1, Histidine triad nucleotide-binding protein 1, PKCI 1, PKCI-1, PKCI1, PRKCNH1, Protein kinase C inhibitor 1, Protein kinase C inter |
| Swissprot | |
| Calculated MW | 14 kDa |
| Cellular Localization | Cytoplasm. Nucleus. Interaction with CDK7 leads to a more nuclear localization. |
| Concentration | 0.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:100-1:300 |
Background
The protein encoded by this gene can hydrolyze substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester, and AMP-NH2. The encoded protein interacts with these substrates via a histidine triad motif, which is part of the loop that binds to the substrate. This gene has been found to be a tumor suppressing gene. Several transcript variants, but only one of them protein-coding, have been found for this gene.