GRIA4 Polyclonal Antibody Host Rabbit
SKU: E-AB-52035-200
GRIA4 Polyclonal Antibody Host Rabbit
| SKU # | E-AB-52035 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human GRIA4 |
| Abbre | GRIA4 |
| Synonyms | AMPA 4, AMPA selective glutamate receptor 4, AMPA-selective glutamate receptor 4, AMPA4, GLUR4C, GLURD, GRIA 4, GRIA4, GluA 4, GluA4, GluR 4, GluR D, GluR-4, GluR-D, GluR4, Glutamate receptor 4, Glutamate receptor ionotrophic AMPA 4, Glutamate receptor ionotropic, Gria4 |
| Swissprot | |
| Cellular Localization | Cell membrane. Cell junction>synapse>postsynaptic cell membrane. |
| Concentration | 1.8 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Neuroscience, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:300 |
Background
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia.