GPT2 Polyclonal Antibody
SKU: E-AB-19961-200
GPT2 Polyclonal Antibody
| SKU # | E-AB-19961 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human GPT2 |
| Abbre | GPT2 |
| Synonyms | AAT2, ALAT2, ALT2, Alanine aminotransferase 2, Glutamate pyruvate transaminase 2, Glutamic alanine transaminase 2, Glutamic pyruvate transaminase (alanine aminotransferase) 2, Glutamic pyruvic transaminase 2, Glutamic--alanine transaminase 2, Glutamic--pyruvic tra |
| Swissprot | |
| Concentration | 2.16 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Metabolism, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:25-1:100 |
Background
This gene encodes a mitochondrial alanine transaminase, a pyridoxal enzyme that catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate.Alanine transaminases play roles in gluconeogenesis and amino acid metabolism in many tissues including skeletal muscle, kidney, and liver.Activating transcription factor 4 upregulates this gene under metabolic stress conditions in hepatocyte cell lines.A loss of function mutation in this gene has been associated with developmental encephalopathy.Alternative splicing results in multiple transcript variants.