Gphn Polyclonal Antibody Store at -20°C
SKU: E-AB-13263-200
Gphn Polyclonal Antibody Store at -20°C
| SKU # | E-AB-13263 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human GPHN |
| Abbre | Gphn |
| Synonyms | Geph |
| Swissprot | |
| Cellular Localization | Cytoskeleton, Plasma Membrane, extrinsic component of cytoplasmic side of plasma membrane, postsynaptic membrane, postsynaptic specialization membrane, Other locations: cell junction, cytoplasm, dendrite, inhibitory synapse, intracellular, neuronal cell body, postsynapse, postsynaptic specialization, synapse. |
| Concentration | 0.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
Gephyrin is a microtubule-associated protein highly expressed in brain and localized to neuronal postsynaptic membranes. Gephyrin is essential for the postsynaptic localization of the inhibitory glycine receptor and is thought to anchor the receptor to subsynaptic microtubules. The protein is expressed in most mammalian tissues with predominant expression in brain. At least five additional splice variants of Gephyrin ranging in molecular weight have been identified in rat and human brain tissue.