GJB6 Polyclonal Antibody Store at -20°C
SKU: E-AB-15680-200
GJB6 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-15680 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human GJB6 |
| Abbre | GJB6 |
| Synonyms | CXB6, Connexin 30, Connexin-30, Cx30, DFNA3, DFNA3B, DFNB1B, ECTD2, ED2, EDH, Gap junct, Gap junction beta 6 protein, Gap junction beta-6 protein, beta 6, beta 6 (connexin 30), ectodermal dysplasia 2, gap junction protein, hidrotic (Clouston syndrome) |
| Swissprot | |
| Cellular Localization | Cell membrane. Cell junction>gap junction. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Neuroscience, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:25-1:100 |
Background
Gap junctions allow the transport of ions and metabolites between the cytoplasm of adjacent cells. They are formed by two hemichannels, made up of six connexin proteins assembled in groups. Each connexin protein has four transmembrane segments, two extracellular loops, a cytoplasmic loop formed between the two inner transmembrane segments, and the N- and C-terminus both being in the cytoplasm. The specificity of the gap junction is determined by which connexin proteins comprise the hemichannel. In the past, connexin protein names were based on their molecular weight, however the new nomenclature uses sequential numbers based on which form (alpha or beta) of the gap junction is present. This gene encodes one of the connexin proteins. Mutations in this gene have been found in some forms of deafness and in some families with hidrotic ectodermal dysplasia.