GFAP Monoclonal Antibody
SKU: E-AB-22022-200
GFAP Monoclonal Antibody
| SKU # | E-AB-22022 |
| Reactivity | Mouse, Rat |
| Host | Mouse |
| Applications | WB, IHC-p, IF |
Product Details
| Isotype | IgG |
| Host | Mouse |
| Reactivity | Mouse, Rat |
| Applications | WB, IHC-p, IF |
| Clonality | Monoclonal |
| Immunogen | Synthetic Peptide |
| Abbre | GFAP |
| Synonyms | ALXDRD, FLJ42474, FLJ45472, GFAP, Glial fibrillary acidic protein, Intermediate filament protein, cb345, etID36982.3, gfapl, wu:fb34h11, wu:fk42c12, xx:af506734, zgc:110485 |
| Swissprot | |
| Calculated MW | 50 kDa |
| Observed MW | 45 kDa |
| Cellular Localization | Cytoplasm |
| Tissue Specificity | Expressed in cells lacking fibronectin |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol. |
| Purification Method | Protein A purification |
| Research Areas | Cancer, Neuroscience, Signal Transduction, Stem Cells, Tags and Cell Markers |
| Clone No. | 3H1 |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:5000 |
| IHC | 1:50-1:300 |
| IF | 1:100-1:300 |
Background
This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms.