FOXL2 Polyclonal Antibody Store at -20°C
SKU: E-AB-15650-200
FOXL2 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-15650 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human FOXL2 |
| Abbre | FOXL2 |
| Synonyms | BPES, BPES 1, BPES1, Blepharophimosis, Blepharophimosis epicanthus inversus and ptosis, Blepharophimosis epicanthus inversus and ptosis 1, Epicanthus inversus and ptosis 1, FOX L2, FOXL 2, Forkhead box L2, Forkhead box protein L2, Forkhead transcription factor FOXL2 |
| Swissprot | |
| Calculated MW | 50 kDa |
| Cellular Localization | Nucleus. |
| Concentration | 0.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
Background
This gene encodes a forkhead transcription factor. The protein contains a fork-head DNA-binding domain and may play a role in ovarian development and function. Mutations in this gene are a cause of blepharophimosis syndrome and premature ovarian failure 3. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9. Activates SIRT1 transcription under cellular stress conditions. Activates transcription of OSR2.