FLNC Polyclonal Antibody
SKU: E-AB-19875-200
FLNC Polyclonal Antibody
| SKU # | E-AB-19875 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human FLNC |
| Abbre | FLNC |
| Synonyms | ABPL, Actin binding like protein, FIlamin 2, FLN2, Filamin C, Gamma filamin |
| Swissprot | |
| Calculated MW | 291 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Cytoplasmic |
| Concentration | 0.96 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:40-1:200 |
Background
This gene encodes one of three related filamin genes, specifically gamma filamin.These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskeleton.Three functional domains exist in filamin: an N-terminal filamentous actin-binding domain, a C-terminal self-association domain, and a membrane glycoprotein-binding domain.Two transcript variants encoding different isoforms have been found for this gene.