EDG3 Polyclonal Antibody Store at -20°C
SKU: E-AB-12921-200
EDG3 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-12921 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human S1PR3 |
| Abbre | S1PR3 |
| Synonyms | EDG 3, EDG3, Endothelial differentiation G protein coupled receptor 3, Endothelial differentiation G-protein coupled receptor 3, Endothelial differentiation gene 3, Endothelial differentiation sphingolipid G protein coupled receptor 3, FLJ37523, FLJ93220, G prote |
| Swissprot | |
| Calculated MW | 42 kDa |
| Cellular Localization | Cell membrane. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cardiovascular, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
Background
This gene encodes a member of the EDG family of receptors, which are G protein-coupled receptors. This protein has been identified as a functional receptor for sphingosine 1-phosphate and likely contributes to the regulation of angiogenesis and vascular endothelial cell function. Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis.