EDA2R Polyclonal Antibody Store at -20°C
SKU: E-AB-11177-200
EDA2R Polyclonal Antibody Store at -20°C
| SKU # | E-AB-11177 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human EDA2R |
| Abbre | EDA2R |
| Synonyms | 9430060M22Rik, EDA A2R, EDA-A2 receptor, EDA2R, EDAA2R, Ectodysplasin A2 isoform receptor, Ectodysplasin A2 receptor, MGC124099, OTTMUSP00000019574, OTTMUSP00000019575, RP23-188N15.1, TNFRSF27, TNR27, Tumor necrosis, Tumor necrosis factor receptor superfamily member 27 |
| Swissprot | |
| Calculated MW | 33 kDa |
| Cellular Localization | Membrane. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Signal Transduction, Stem Cells |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:50-1:200 |
Background
EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that are encoded by the anhidrotic ectodermal dysplasia (EDA) gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. The protein encoded by this gene specifically binds to EDA-A2 isoform. This protein is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. Alternatively spliced transcript variants have been found for this gene.