CXCR4 Polyclonal Antibody Store at -20°C
SKU: E-AB-11047-200
CXCR4 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-11047 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human CXCR4 |
| Abbre | CXCR4 |
| Synonyms | C-X-C chemokine receptor type 4, CD184, CD184 antigen, CXC-R4, CXCR-4, CXCR4, Chemokine (C X C motif) receptor 4, Chemokine CXC Motif Receptor 4, D2S201E, FB22, Fusin, HM89, HSY3RR, LAP 3, LAP3, LCR1, LESTR, Leuk, Leukocyte derived seven transmembrane domain receptor |
| Swissprot | |
| Cellular Localization | Cell membrane. In unstimulated cells, diffuse pattern on plasma membrane. On agonist stimulation, colocalizes with ITCH at the plasma membrane where it becomes ubiquitinated. |
| Concentration | 0.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Metabolism, Immunology, Microbiology, Neuroscience, Stem Cells |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1.The protein has 7 transmembrane regions and is located on the cell surface.It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells.Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome.Alternate transcriptional splice variants, encoding different isoforms, have been characterized.