CRHR2 Polyclonal Antibody Store at -20°C Host Rabbit
SKU: E-AB-16358-200
CRHR2 Polyclonal Antibody Store at -20°C Host Rabbit
| SKU # | E-AB-16358 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human CRHR2 |
| Abbre | CRHR2 |
| Synonyms | CRF 2, CRF 2R, CRF R2, CRF RB, CRF-R-2, CRF-R2, CRF2, CRF2 receptor beta isoform, CRF2R, CRFR 2, CRFR-2, CRFR2, CRH 2R, CRH R2, CRH-R-2, Corticotropin releasing hormone receptor 2, Corticotropin-releasing factor receptor 2, Corticotropin-releasing hormone receptor 2 |
| Swissprot | |
| Calculated MW | 48 kDa |
| Cellular Localization | Cell membrane. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Neuroscience |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:200-1:1000 |
Background
The protein encoded by this gene belongs to the G-protein coupled receptor 2 family, and the subfamily of corticotropin releasing hormone receptor. This receptor shows high affinity for corticotropin releasing hormone (CRH), and also binds CRH-related peptides such as urocortin. CRH is synthesized in the hypothalamus, and plays an important role in coordinating the endocrine, autonomic, and behavioral responses to stress and immune challenge. Studies in mice suggest that this receptor maybe involved in mediating cardiovascular homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.