CREB1 Monoclonal Antibody
SKU: E-AB-22113-200
CREB1 Monoclonal Antibody
| SKU # | E-AB-22113 |
| Reactivity | Human, Mouse |
| Host | Mouse |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Mouse |
| Reactivity | Human, Mouse |
| Applications | WB |
| Clonality | Monoclonal |
| Immunogen | Recombinant Protein |
| Abbre | CREB-1 |
| Synonyms | Active transcription factor CREB, CREB, CREB-1, CREB1, Cyclic AMP-responsive element-bindin, cAMP response element binding protein, cAMP response element binding protein 1, cAMP responsive element binding protein 1, cAMP-responsive element-binding protein 1 |
| Swissprot | |
| Observed MW | 43 kDa |
| Cellular Localization | Nucleus. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol. |
| Purification Method | Protein A purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling, Immunology |
| Clone No. | 3F1 |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1000 |
Background
This protein binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. CREB stimulates transcription on binding to the CRE. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Implicated in synchronization of circadian rhythmicity.