COX6B1 Polyclonal Antibody Store at -20°C
SKU: E-AB-10074-200
COX6B1 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-10074 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human COX6B1 |
| Abbre | COX6B1 |
| Synonyms | COX 6B, COX VIb 1, COX VIb-1, COX6B, COX6B1, COXG, COXVIb1, CX6B1, Cytochrome c oxidase subuni, Cytochrome c oxidase subunit 6B1, Cytochrome c oxidase subunit VIb, Cytochrome c oxidase subunit VIb isoform 1, cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) |
| Swissprot | |
| Calculated MW | 10 kDa |
| Cellular Localization | Mitochondrion intermembrane space. |
| Concentration | 0.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Metabolism, Signal Transduction, Tags and Cell Markers |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:1000-1:5000 |
| IHC | 1:50-1:200 |
Background
Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIb. Mutations in this gene are associated with severe infantile encephalomyopathy. Three pseudogenes COX6BP-1, COX6BP-2 and COX6BP-3 have been found on chromosomes 7, 17 and 22q13.1-13.2, respectively.