Claudin 7 Polyclonal Antibody Store at -20°C
SKU: E-AB-15677-200
Claudin 7 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-15677 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human CLDN7 |
| Abbre | CLDN7 |
| Synonyms | CEPTR L2, CEPTRL 2, CEPTRL2, CLD7, CLDN 7, CLDN-7, CLDN7, CPETR L2, CPETRL 2, CPETRL2, Claudin 1, Claudin 9, Claudin-7, Claudin1, Claudin7, Claudin9, Clostridium perfringens enterotoxin receptor like 2, Hs.84359 |
| Swissprot | |
| Calculated MW | 23 kDa |
| Cellular Localization | Cell membrane. Lateral cell membrane. Cell junction>tight junction. Co-localizes with EPCAM at the lateral cell membrane and tight junction. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:1000-1:3000 |
| IHC | 1:50-1:150 |
Background
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc. Alternatively spliced transcript variants encoding different isoforms have been found.