CITED4 Polyclonal Antibody
SKU: E-AB-19707-200
CITED4 Polyclonal Antibody
| SKU # | E-AB-19707 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human CITED4 |
| Abbre | CITED4 |
| Synonyms | 4, with glu/asp rich carboxy terminal domain, AU019445, AW742964, CITE4, Cbp/p300 interacting transactivator 4, Cbp/p300-interacting transactivator 4, Cited4, MRG 2, MRG-2, MSG1 related protein 2, MSG1-related protein 2, Mrg2, Tra, cbp/p300 interacting transactivator |
| Swissprot | |
| Cellular Localization | Nucleus. Cytoplasm. |
| Concentration | 0.9 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling, Metabolism |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:30-1:150 |
Background
The protein encoded by this intronless gene belongs to the CITED family of transcriptional coactivators that bind to several proteins, including CREB-binding protein (CBP) and p300, via a conserved 32 aa C-terminal motif, and regulate gene transcription.This protein also interacts with transcription factor AP2 (TFAP2), and thus may function as a co-activator for TFAP2.Hypermethylation and transcriptional downregulation of this gene has been observed in oligodendroglial tumors with deletions of chromosomal arms 1p and 19q, and associated with longer recurrence-free and overall survival of patients with oligodendroglial tumors.