CDK11A/B Polyclonal Antibody
SKU: E-AB-16328-200
CDK11A/B Polyclonal Antibody
| SKU # | E-AB-16328 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human CDK11A/CDK11B |
| Abbre | CDK11A/CDK11B |
| Synonyms | CDC2L1, CDC2L2, CDC2L3, CDK11, CDK11-p110, CDK11-p110 / p58, CDK11-p46, CDK11-p58, CLK-1, PITSLRE, PK58, p58CDC2L1, p58CLK-1, p58GTA |
| Swissprot | |
| Cellular Localization | Nucleus, Other locations: cytoplasm. |
| Concentration | 0.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
Cyclin-dependent kinases (CDKs) are a family of protein kinases first discovered for their role in regulating the cell cycle.They are also involved in regulating transcription, mRNA processing, and the differentiation of nerve cells.They are present in all known eukaryotes, and their regulatory function in the cell cycle has been evolutionarily conserved.CDKs are relatively small proteins, witHuman, Mouseolecular weights ranging from 34 to 40 kDa, and contain little more than the kinase domain.By definition, a CDK binds a regulatory protein called a cyclin.Without cyclin, CDK has little kinase activity; only the cyclin-CDK complex is an active kinase.CDKs phosphorylate their substrates on serines and threonines, so they are serine-threonine kinases.