CD206 Polyclonal Antibody
SKU: E-AB-33717-200
CD206 Polyclonal Antibody
| SKU # | E-AB-33717 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | WB, IHC-p |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | WB, IHC-p |
| Clonality | Polyclonal |
| Immunogen | Synthesized peptide derived from the Internal region of human CD206. |
| Abbre | CD206 |
| Synonyms | C type lectin domain family 13 member D, C-type lectin domain family 13 member D, CD 206, CD206, CD206 antigen, CLEC13D, CLEC13DL, Macrophage mannose receptor, Macrophage mannose receptor 1, Macrophage mannose receptor 1 like protein 1, Mannose receptor , bA541I19.1 |
| Swissprot | |
| Calculated MW | 166 kDa |
| Observed MW | 170 kDa |
| Cellular Localization | Membrane. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Immunology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:100-1:300 |
Background
The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.