CA11 Polyclonal Antibody Reactivity Human
SKU: E-AB-52516-200
CA11 Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52516 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human CA11 |
| Abbre | CA11 |
| Synonyms | CA-RP II, CA-RP XI, CA-XI, CA11, CAH11, CARP XI, CARP-2, CARP2, Carbonic anhydrase-related protein 11, Carbonic anhydrase-related protein 2 |
| Swissprot | |
| Cellular Localization | Secreted. |
| Concentration | 0.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cell Biology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:30-1:150 |
Background
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide.They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid.They show extensive diversity in tissue distribution and in their subcellular localization.CA XI is likely a secreted protein, however, radical changes at active site residues completely conserved in CA isozymes with catalytic activity, make it unlikely that it has carbonic anhydrase activity.It shares properties in common with two other acatalytic CA isoforms, CA VIII and CA X.CA XI is most abundantly expressed in brain, and may play a general role in the central nervous system.