BRK1 Polyclonal Antibody Store at -20°C Host Rabbit
SKU: E-AB-16477-200
BRK1 Polyclonal Antibody Store at -20°C Host Rabbit
| SKU # | E-AB-16477 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human BRK1 |
| Abbre | BRK1 |
| Synonyms | BRICK1, BRK1, Brk1-like, C3ORF10 GENE, C3orf10 chromosome 3 open reading frame 10, Chromosome 3 open reading frame 10, Haematopoietic stem/progenitor cell prote, SCAR/WAVE actin nucleating complex subunit, homolog |
| Swissprot | |
| Cellular Localization | Cytoplasm, cytoskeleton. |
| Concentration | 0.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
HSPC300 (hematopoietic stem cell protein 300) is also known as probable protein BRICK1 or C3orf10 (chromosome 3 open reading frame 10) and is a 75 amino acid protein that is expressed as two isoforms and localizes to both the cytoplasm and the cytoskeleton.HSPC300 is thought to regulate cytoskeletal organization and Actin polymerization.Free HSPC300 exists as homotrimers prior to its incorporation into the WAVE complex.The WAVE complex includes five proteins, one of which is HSPC300, that regulate the ARC (Arp2/3 complex) which is responsible for Actin nucleation and is Rac 1-dependent.Because HSPC300 is a highly conserved subunit of the WAVE complex across many species, it is thought to have the same or similar functions in many different organisms.