BRD4 Polyclonal Antibody Store at -20°C
SKU: E-AB-13037-200
BRD4 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-13037 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human BRD4 |
| Abbre | BRD4 |
| Synonyms | BRD4, BRD4-NUT FUSION, BRD4-NUT fusion oncoprotein, Brd4, Bromodomain containing 4, Bromodomain-containing protein 4, CAP, HUNK1, HUNKI, MCAP, Mitotic chromosome-associated protein, Protein HUNK1, bromodomain containing protein 4, chromosome associated protein |
| Swissprot | |
| Calculated MW | 152 kDa |
| Cellular Localization | Nucleus. |
| Concentration | 0.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
Background
The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif whicHuman, Mouseay be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described.