ASCC2 Polyclonal Antibody Store at -20°C
SKU: E-AB-16227-200
ASCC2 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-16227 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human ASCC2 |
| Abbre | ASCC2 |
| Synonyms | 1700011I11Rik, 2610034L15Rik, AI482016, ASC 1 complex subunit p100, ASC-1 complex subunit p100, ASC1P100, ASCC 2, ASCC2, AW046480, Activating signal cointegrator 1 complex subunit 2, Ascc2, FLJ21588, OTTMUSP00000005258, RGD1561422, RP23-280J3.3, Trip4 complex subun, p100 |
| Swissprot | |
| Calculated MW | 86 kDa |
| Cellular Localization | Nucleus, nucleoplasm, nucleus, Other locations: activating signal cointegrator 1 complex. |
| Concentration | 0.7 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
Background
ASCC2 (activating signal cointegrator 1 complex subunit 2), also known as ASC1P100, is a 757 amino acid protein that is ubiquitously expressed and contains one CUE domain.The gene encoding ASCC2 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias.