ARHGEF11 Polyclonal Antibody Store at -20°C
SKU: E-AB-16180-200
ARHGEF11 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-16180 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human ARHGEF11 |
| Abbre | ARHGEF11 |
| Synonyms | ARHGB, ARHGEF 11, ARHGEF11, DKFZp667F1223, GTRAP 48, GTRAP48, Glutamate transporter EAAT4 associated protein 48, KIAA0380, OTTHUMP00000038716, OTTHUMP00000038717, PDZ RHOGEF, PDZ-RhoGEF, Rho guanine exchange factor (GEF) 11, Rho guanine nucleotide exchange factor (GEF |
| Swissprot | |
| Calculated MW | 168 kDa |
| Cellular Localization | Cytoplasm. Membrane. Translocated to the membrane upon stimulation. |
| Concentration | 0.8 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
Background
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described.